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projects [2015/08/11 15:25] jarekprojects [2015/08/11 21:02] jarek
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-====== Proposed Projects for Fall 2014 ======+====== Proposed Projects for Fall 2015 ======
 \\ \\
  
-===Dynamic Interface Detection and Control Project===+=====Data visualization in Skydive===== 
 + 
 +**Supervisor: Jarek Gryz** 
 + 
 +Skydive is a prototype system designed for database visualization using a concept of the so called 
 +data pyramid. The system is composed of three modules (DB - Database Module, D2I - 
 +Data-to-Image module, and VC - Visualizaton Client). Each is designed to use a different type 
 +of computer memory. The DB module uses disk to store and manage the raw data, and materialized 
 +data pyramids. The D2I module works with a small subset of the aggregated dataset, 
 +and stores data in main memory (RAM). The VC module uses the graphic card’s capabilities to 
 +perform more advanced operations – such as zooming, scaling, panning, and rotation – over the 
 +graphical representation of the data. 
 +Currently the system support three presentation models implemented within the Visualization 
 +Component, namely: 
 + 
 +• a 2D heat-map; 
 + 
 +• a 2.5 D heat-map by 3D barchart; and 
 + 
 +• a 2.5 D terrain (by mesh and UV-mapping). 
 + 
 +The goal of the project is to implement two additional ways of data visualization as well as 
 +extend some of existing ones, that is: 
 + 
 +1. Implement and test functions for data pyramid-based visualization of time series. 
 + 
 +2. Implement functions for visualization based on cross-product of data pyramids. 
 + 
 +3. Add support for specular and normal maps for 2.5 D terrain presentation model. 
 + 
 +Required Background: CSE 3421, Java programming course, (C programming course a plus) 
 + 
 + 
 +\\ 
 +=====Genome-wide identification of plant micro RNAs===== 
 + 
 + 
 +**Supervisor: Katalin Hudak** 
 + 
 + 
 +The Hudak Lab in the Biology Department has an opening for a fourth-year Honours student to assist with a bioinformatics project. We study the pokeweed plant, Phytolacca americana, which displays broad-spectrum virus resistance. To evaluate pokeweed gene expression, we recently sequenced the plant’s mRNA and small RNA transcriptomes under jasmonic acid (JA) treatment. JA is a plant hormone that mediates defence against pathogens and insect herbivores. We are interested in learning how pokeweed gene expression is regulated by miRNAs during biotic stress.  Please note: no previous knowledge of biology is required.  
 + 
 +Working with the support of a PhD student, your project will involve: 
 + 
 +1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches 
 + 
 +2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs 
 + 
 +3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs 
 + 
 +4) Construction of a miRNA/target interaction network to visualize predictions 
 +This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA. 
 + 
 +Requirements: 
 + 
 +1) Pre-requisites as per EECS Calendar 
 + 
 +2) Facility with script-writing/modification (in Perl or Python) 
 + 
 +3) Preference for students with knowledge of statistics and familiarity with R programming 
 + 
 +4) Able to begin in September 2015 
 + 
 +Learning outcomes: 
 + 
 +1) Manipulate and analyze quantitative biological data 
 + 
 +2) Develop and test hypotheses by modifying existing software and writing new script 
 + 
 +3) Manage a CentOS computer server to store and facilitate ongoing research  
 + 
 +No knowledge of biology is required.  
 + 
 +For more information, please see: 
 + Hudak Lab website- http://hudak.lab.yorku.ca/ 
 + 
 +RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html 
 + 
 +miRNAs- http://en.wikipedia.org/wiki/MicroRNA 
 + 
 +\\ 
 +=====Dynamic Interface Detection and Control Project=====
  
 **Supervisor: Michael Jenkin** **Supervisor: Michael Jenkin**
projects.txt · Last modified: 2016/01/13 20:05 by stevenc