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projects [2015/08/11 20:42] jarekprojects [2015/08/11 20:43] jarek
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-====== Proposed Projects for Fall 2014 ======+====== Proposed Projects for Fall 2015 ======
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 Working with the support of a PhD student, your project will involve: Working with the support of a PhD student, your project will involve:
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 1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches 1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches
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 2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs 2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs
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 3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs 3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs
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 4) Construction of a miRNA/target interaction network to visualize predictions 4) Construction of a miRNA/target interaction network to visualize predictions
 This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA. This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA.
  
 Requirements: Requirements:
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 1) Pre-requisites as per EECS Calendar 1) Pre-requisites as per EECS Calendar
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 2) Facility with script-writing/modification (in Perl or Python) 2) Facility with script-writing/modification (in Perl or Python)
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 3) Preference for students with knowledge of statistics and familiarity with R programming 3) Preference for students with knowledge of statistics and familiarity with R programming
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 4) Able to begin in September 2015 4) Able to begin in September 2015
  
 Learning outcomes: Learning outcomes:
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 1) Manipulate and analyze quantitative biological data 1) Manipulate and analyze quantitative biological data
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 2) Develop and test hypotheses by modifying existing software and writing new script 2) Develop and test hypotheses by modifying existing software and writing new script
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 3) Manage a CentOS computer server to store and facilitate ongoing research  3) Manage a CentOS computer server to store and facilitate ongoing research 
  
 No knowledge of biology is required.  No knowledge of biology is required. 
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 For more information, please see: For more information, please see:
  Hudak Lab website- http://hudak.lab.yorku.ca/  Hudak Lab website- http://hudak.lab.yorku.ca/
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 RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html
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 miRNAs- http://en.wikipedia.org/wiki/MicroRNA miRNAs- http://en.wikipedia.org/wiki/MicroRNA
  
projects.txt · Last modified: 2016/01/13 20:05 by stevenc