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projects [2015/08/11 20:42] jarekprojects [2015/08/11 21:02] jarek
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-====== Proposed Projects for Fall 2014 ======+====== Proposed Projects for Fall 2015 ======
 \\ \\
  
-===Genome-wide identification of plant micro RNAs===+=====Data visualization in Skydive===== 
 + 
 +**Supervisor: Jarek Gryz** 
 + 
 +Skydive is a prototype system designed for database visualization using a concept of the so called 
 +data pyramid. The system is composed of three modules (DB - Database Module, D2I - 
 +Data-to-Image module, and VC - Visualizaton Client). Each is designed to use a different type 
 +of computer memory. The DB module uses disk to store and manage the raw data, and materialized 
 +data pyramids. The D2I module works with a small subset of the aggregated dataset, 
 +and stores data in main memory (RAM). The VC module uses the graphic card’s capabilities to 
 +perform more advanced operations – such as zooming, scaling, panning, and rotation – over the 
 +graphical representation of the data. 
 +Currently the system support three presentation models implemented within the Visualization 
 +Component, namely: 
 + 
 +• a 2D heat-map; 
 + 
 +• a 2.5 D heat-map by 3D barchart; and 
 + 
 +• a 2.5 D terrain (by mesh and UV-mapping). 
 + 
 +The goal of the project is to implement two additional ways of data visualization as well as 
 +extend some of existing ones, that is: 
 + 
 +1. Implement and test functions for data pyramid-based visualization of time series. 
 + 
 +2. Implement functions for visualization based on cross-product of data pyramids. 
 + 
 +3. Add support for specular and normal maps for 2.5 D terrain presentation model. 
 + 
 +Required Background: CSE 3421, Java programming course, (C programming course a plus) 
 + 
 + 
 +\\ 
 +=====Genome-wide identification of plant micro RNAs=====
  
  
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 Working with the support of a PhD student, your project will involve: Working with the support of a PhD student, your project will involve:
 +
 1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches 1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches
 +
 2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs 2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs
 +
 3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs 3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs
 +
 4) Construction of a miRNA/target interaction network to visualize predictions 4) Construction of a miRNA/target interaction network to visualize predictions
 This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA. This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA.
  
 Requirements: Requirements:
 +
 1) Pre-requisites as per EECS Calendar 1) Pre-requisites as per EECS Calendar
 +
 2) Facility with script-writing/modification (in Perl or Python) 2) Facility with script-writing/modification (in Perl or Python)
 +
 3) Preference for students with knowledge of statistics and familiarity with R programming 3) Preference for students with knowledge of statistics and familiarity with R programming
 +
 4) Able to begin in September 2015 4) Able to begin in September 2015
  
 Learning outcomes: Learning outcomes:
 +
 1) Manipulate and analyze quantitative biological data 1) Manipulate and analyze quantitative biological data
 +
 2) Develop and test hypotheses by modifying existing software and writing new script 2) Develop and test hypotheses by modifying existing software and writing new script
 +
 3) Manage a CentOS computer server to store and facilitate ongoing research  3) Manage a CentOS computer server to store and facilitate ongoing research 
  
 No knowledge of biology is required.  No knowledge of biology is required. 
 +
 For more information, please see: For more information, please see:
  Hudak Lab website- http://hudak.lab.yorku.ca/  Hudak Lab website- http://hudak.lab.yorku.ca/
 +
 RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html
 +
 miRNAs- http://en.wikipedia.org/wiki/MicroRNA miRNAs- http://en.wikipedia.org/wiki/MicroRNA
  
 \\ \\
- +=====Dynamic Interface Detection and Control Project=====
- +
-===Dynamic Interface Detection and Control Project===+
  
 **Supervisor: Michael Jenkin** **Supervisor: Michael Jenkin**
projects.txt · Last modified: 2016/01/13 20:05 by stevenc