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projects [2015/08/11 20:42] jarekprojects [2015/08/17 12:02] jarek
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-====== Proposed Projects for Fall 2014 ======+====== Proposed Projects for Fall 2015 ======
 \\ \\
  
-===Genome-wide identification of plant micro RNAs===+=====Data visualization in Skydive===== 
 + 
 +**Supervisor: Jarek Gryz** 
 + 
 +Skydive is a prototype system designed for database visualization using a concept of the so called 
 +data pyramid. The system is composed of three modules (DB - Database Module, D2I - 
 +Data-to-Image module, and VC - Visualizaton Client). Each is designed to use a different type 
 +of computer memory. The DB module uses disk to store and manage the raw data, and materialized 
 +data pyramids. The D2I module works with a small subset of the aggregated dataset, 
 +and stores data in main memory (RAM). The VC module uses the graphic card’s capabilities to 
 +perform more advanced operations – such as zooming, scaling, panning, and rotation – over the 
 +graphical representation of the data. 
 +Currently the system support three presentation models implemented within the Visualization 
 +Component, namely: 
 + 
 +• a 2D heat-map; 
 + 
 +• a 2.5 D heat-map by 3D barchart; and 
 + 
 +• a 2.5 D terrain (by mesh and UV-mapping). 
 + 
 +The goal of the project is to implement two additional ways of data visualization as well as 
 +extend some of existing ones, that is: 
 + 
 +1. Implement and test functions for data pyramid-based visualization of time series. 
 + 
 +2. Implement functions for visualization based on cross-product of data pyramids. 
 + 
 +3. Add support for specular and normal maps for 2.5 D terrain presentation model. 
 + 
 +Required Background: CSE 3421, Java programming course, (C programming course a plus) 
 + 
 + 
 +\\ 
 +=====Genome-wide identification of plant micro RNAs=====
  
  
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 Working with the support of a PhD student, your project will involve: Working with the support of a PhD student, your project will involve:
 +
 1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches 1) Prediction of micro RNA (miRNA) targets on the basis of complementary sequence matches
 +
 2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs 2) Correlation of miRNA and mRNA expression changes to identify genes that are regulated by miRNAs
 +
 3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs 3) Conducting pathway analysis to determine which biological processes are controlled by miRNAs
 +
 4) Construction of a miRNA/target interaction network to visualize predictions 4) Construction of a miRNA/target interaction network to visualize predictions
 This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA. This work will contribute to a scientific manuscript on miRNA-mediated gene regulation in pokeweed during response to JA.
  
 Requirements: Requirements:
 +
 1) Pre-requisites as per EECS Calendar 1) Pre-requisites as per EECS Calendar
 +
 2) Facility with script-writing/modification (in Perl or Python) 2) Facility with script-writing/modification (in Perl or Python)
 +
 3) Preference for students with knowledge of statistics and familiarity with R programming 3) Preference for students with knowledge of statistics and familiarity with R programming
 +
 4) Able to begin in September 2015 4) Able to begin in September 2015
  
 Learning outcomes: Learning outcomes:
 +
 1) Manipulate and analyze quantitative biological data 1) Manipulate and analyze quantitative biological data
 +
 2) Develop and test hypotheses by modifying existing software and writing new script 2) Develop and test hypotheses by modifying existing software and writing new script
 +
 3) Manage a CentOS computer server to store and facilitate ongoing research  3) Manage a CentOS computer server to store and facilitate ongoing research 
  
 No knowledge of biology is required.  No knowledge of biology is required. 
 +
 For more information, please see: For more information, please see:
  Hudak Lab website- http://hudak.lab.yorku.ca/  Hudak Lab website- http://hudak.lab.yorku.ca/
 +
 RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html RNA sequencing- http://www.illumina.com/applications/sequencing/rna.html
 +
 miRNAs- http://en.wikipedia.org/wiki/MicroRNA miRNAs- http://en.wikipedia.org/wiki/MicroRNA
  
 \\ \\
- +=====Dynamic Interface Detection and Control Project=====
- +
-===Dynamic Interface Detection and Control Project===+
  
 **Supervisor: Michael Jenkin** **Supervisor: Michael Jenkin**
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 \\  \\ 
-====== Hunting for Bugs in Logging: applying JPF to log4j ======+====== JPF in a Jar ======
  
 **Supervisor:** Franck van Breugel **Supervisor:** Franck van Breugel
  
 Description: Description:
-Java PathFinder (JPF) is tool that can detect bugs in Java code. +JPF, which is short for Java PathFinderis an open source 
-The Java library Apache log4j allows developers to control which log +tool that has been developed at NASA's Ames Research Center. 
-statements are output.  In the pastDickey et al. [1] have attempted +The aim of JPF is to find bugs in Java code.  Instead of  
-to detect bugs in log4j by means of JPF with very limited succes.+using testing to find those bugs, JPF uses model checking
 +The facts that JPF is downloaded hundreds of times per month 
 +and that some of the key papers on JPF have been cited more  
 +than a thousand times reflect the popularity of JPF. In 
 +fact it is the most popular model checker for Java
 + 
 +A study done by Cambridge University in 2014 found that the  
 +global cost of debugging code has risen to $312 billion annually.  
 +Furthermore, on average software developers spend 50% of their  
 +programming time with finding and fixing bugs.  As a consequence,  
 +advocating the use toolssuch as JPF, may have significant impact. 
 + 
 +Installing JPF is far from trivial.  The tool itself has been 
 +implemented in Java.  Therefore, it should, in theory, be  
 +feasible to encapsulate JPF in a Java archive (jar) file.   
 +This would make it significantly simplifying the installation  
 +process of JPF and, therefore, make the tool more easily  
 +accessible to its potential users.
  
-Recently, in collaboration with Shafiei (NASA) we have developed +The aim of this project is to attempt to put JPF in a jar. 
-an extension of JPF called jpf-nhandler.  The aim of this project +Since JPF relies on a number of configuration files, so-called 
-is to apply this extension to log4j.+Java properties files, incorporating these properly into the 
 +jar is one of the challenges.  Setting JPF's classpath is 
 +another challenge.  Since JPF changes almost on a daily basis, 
 +our modifications to JPF should ideally be limited to only a  
 +few classes, yet another challenge.
  
-[1] David ADickey, BSinem Dorter, JMichael German, Benjamin DMadoreMark WPiper, Gabriel LZenarosa. "Evaluating Java PathFinder on Log4J."  2011.+In this project you may collaborate with graduate students  
 +of the DisCoVeri group (discoveri.eecs.yorku.ca) and  
 +computer scientists of NASA For more informationfeel 
 +free to send email to franck@cse.yorku.ca.
  
 **Required Background:** General CSE408x prerequisites **Required Background:** General CSE408x prerequisites
projects.txt · Last modified: 2016/01/13 20:05 by stevenc