Differences

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--- geneonyxmar302012:start [2015/05/06 03:49] – magiero
+++ geneonyxmar302012:start [2015/05/06 03:53] (current) – magiero
@@ Line 46: / Line 46: @@
 • Ostensibly the primer (of length n) binds to the DNA at the predetermined spot (defined by the sequence of the primer itself).\\
 • The chamber containing the nt that complements the SNP (in the n+1 position) will then undergo a hydrolisis reaction that drops the pH and is detected by an ISFET.\\
-•
+• The ISFET's (one per chamber) are **cleverly interfaced** (__this is basically the invention__) to four differential amps (based on knowledge of allele possibilities in mammals) which produce signal combinations such that the type of SNP encountered can be identified.\\
+• This arrangement reduces the effect of offsets and the need for extensive, high-resolution sampling.
 ==== - Detailed Description ====