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oxfordapr202009b:start [2015/02/06 14:09] magierooxfordapr202009b:start [2015/11/06 02:42] (current) magiero
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 • [0099] **Output pump** 34 pumps fluids out of the sensor through **outlet channel** 36 (connected to **waste reservoir** 35 on the bottom).\\ • [0099] **Output pump** 34 pumps fluids out of the sensor through **outlet channel** 36 (connected to **waste reservoir** 35 on the bottom).\\
 • [0100] **Selector valve** 45 connects the sensor to either the supply or the waste reservoir.\\ • [0100] **Selector valve** 45 connects the sensor to either the supply or the waste reservoir.\\
 +
 +{{ cartridge2bot.png?300}}
 +{{cartridge2.png?300}}
 +{{wellplate.png?200}}
  
 ==== - Three Sensor-on-PCB Alternatives [0148] - [0151] ==== ==== - Three Sensor-on-PCB Alternatives [0148] - [0151] ====
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 === - The Control Function [0176]-[0203] === === - The Control Function [0176]-[0203] ===
 • [0176] The control function is distributed between the internal board 50 and embedded computer 51.\\ • [0176] The control function is distributed between the internal board 50 and embedded computer 51.\\
-• [0177] The control function includes a controller 58, for example a [[http://www.arm.com/products/processors/cortex-m/cortex-m3.php|Cortex M3 microcontroller]], provided on the internal board 50.\\ +• [0177] The control function includes a **controller** 58, for example a [[http://www.arm.com/products/processors/cortex-m/cortex-m3.php|Cortex M3 microcontroller]], provided on the internal board 50.\\ 
-• +• [0178] Controller 50 itself controlled by **control module** 80 implemented in embedded computer 51.  50 and 80 communicate via RS232 81.\\ 
 +• [0201] The analysis apparatus 13 (where is this 13?!?!?!) may contain **control DNA** spiked into real samples.  Data from the control DNA can be used to adjust and refine the algorithms.
  
 ==== - Cluster of Modules [0204] - [0243] ==== ==== - Cluster of Modules [0204] - [0243] ====
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 ==== - Specifics on Sequencing Example 1 [0261] - [0275] ==== ==== - Specifics on Sequencing Example 1 [0261] - [0275] ====
  
-==== - Details of Biochemical Analysis that can be Performed [0276] - [] ====+==== - Details of Biochemical Analysis that can be Performed [0276] - [0298] ====
  
 • [0282] nanopore-assisted sequencing by hydridisation; strand sequencing; and exonuclease-nanopore sequencing\\ • [0282] nanopore-assisted sequencing by hydridisation; strand sequencing; and exonuclease-nanopore sequencing\\
 • [0284]  External circuitry can then perform measurements of DNA passing through each and every nanopore in the array **without the synchronization of base addition** to each nanopore in the array, i.e. each nanopore is free to process a single DNA strand independently of every other, for example as disclosed in [[oxforddec192007:start | Dec. 19, 2007 patent]].\\ • [0284]  External circuitry can then perform measurements of DNA passing through each and every nanopore in the array **without the synchronization of base addition** to each nanopore in the array, i.e. each nanopore is free to process a single DNA strand independently of every other, for example as disclosed in [[oxforddec192007:start | Dec. 19, 2007 patent]].\\
 +• [0284] Having processes one strand, each nanopore is also then free to begin processing a subsequent strand.\\
oxfordapr202009b/start.1423231749.txt.gz · Last modified: 2015/02/06 14:09 by magiero

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